Helcococcus kunzii methyltransferase Erm(47) responsible for MLSB resistance is induced by diverse ribosome-targeting antibiotics
نویسندگان
چکیده
منابع مشابه
Prosthetic joint infection caused by Helcococcus kunzii.
Helcococcus kunzii was isolated by sonication and conventional cultures obtained from a case of infection following total knee prosthesis in an immunocompetent patient. The patient recovered uneventfully. This is the first known case of an H. kunzii prosthetic joint infection.
متن کاملBreast abscess associated with Helcococcus kunzii.
Helcococcus kunzii, a nonvirulent member of the human skin flora, has recently been implicated in causing infections in immunosuppressed patients. We report a case of breast abscess associated with H. kunzii in an immunocompetant patient and discuss the criteria used in its identification and our observations of susceptibility testing for this species.
متن کاملPdtaS Deficiency Affects Resistance of Mycobacteria to Ribosome Targeting Antibiotics
Two-component regulatory systems (TCSSs) are key regulatory elements responsible for the adaptation of bacteria to environmental stresses. A classical TCSS is typically comprised of a sensory histidine kinase and a corresponding response regulator. Here, we used homologous recombination to construct a Mycobacterium smegmatis mutant defective in the synthesis of cytosolic histidine kinase PdtaS ...
متن کاملHelcococcus kunzii isolated from a sow with purulent urocystitis.
Helcococcus kunzii has never been reported in veterinary medicine. The isolation of H. kunzii from a sow with purulent urocystitis is described, suggesting this organism's potential pathogenic role in swine.
متن کاملIdentification and Clinical Significance of Helcococcus kunzii in Human Samples.
From 2008 to 2013, 39 Helcococcus kunzii strains were collected from human clinical specimens (79% from foot ulcers), and 85% of the 39 patients were infected. Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry and molecular methods accurately identified all isolates. This large study of clinical observations confirms the potential pathogenic role of H. kun...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2019
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkz441